POINeT: protein interactome with sub-network analysis and hub prioritization
نویسندگان
چکیده
منابع مشابه
Plant Protein-Protein Interaction Network and Interactome
Protein-protein interaction network represents an important aspect of systems biology. The understanding of the plant protein-protein interaction network and interactome will provide crucial insights into the regulation of plant developmental, physiological, and pathological processes. In this review, we will first define the concept of plant interactome and the protein-protein interaction netw...
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Proteins are important players in executing the genetic program. When carrying out a particular biological function or serving as molecular building blocks for a particular cellular structure, proteins rarely act individually. Rather, biological complexity is encapsulated in the structure and dynamics of the combinatorial interactions among proteins as well as other biological molecules (such a...
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High-throughput techniques involve large-scale detection of protein-protein interactions. This interaction data set from the genome-scale perspective is structured into an interactome network. Since the interaction evidence represents functional linkage, various graph-theoretic computational approaches have been applied to the interactome networks for functional characterization. However, this ...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2009
ISSN: 1471-2105
DOI: 10.1186/1471-2105-10-114